Farmakologiset mittalaitteet
Tuotantolaite / simulointilaite
AR 403 R&D tuotantolaite
The ERWEKA All-Purpose system is based on a powerful drive unit available in two versions. The various attachments can be easily and quickly connected by means of a coupling.
The drive unit AR 403 is equipped with a three-phase AC motor. The sturdy ball bearing worm gear drive is completely maintenance free and provides an output torque of max. 23 Nm. The unit features electronic speed control, variable between 20 and 400 rpm. A digital dial regulates the speed.
Through permanent nominal/actual adjustment the preselected speed is kept, even under varying load. The AR 403-S is similar to the AR 403, but has a different drive train. This connection is designed for heavy use.
R&D and Small Scale Production – The ideal solution
ERWEKA’s All-Purpose equipment is ideal for small scale production in the pharmaceutical, chemical, cosmetic and food industries. In addition, it fits perfect into R&D and the development of powder tablets, ointments, crèmes and more. The modular design is compact, economical and offers a powerful motor drive with a wide ideal for R&D and small scale production range of easily interchangeable attachments for various purposes.
Universal Gear – Extends for even more
The universal gear is required for adjusting the angle of operation (0-80°) and for speed reduction (1:6).
The UG is required for the operation of
- Coating pan (DKE/S)
- Polishing drum (PT)
- Cube mixer (KB 15/20/S)
- Pelletizer (GTE)
- Ball mills (KM 0)
- Double cone mixer (DKM)
Hajoamismittalaitteet
ZT 120 hajoamismittalaite
The ERWEKA ZT 120 light series is the perfect entry-level disintegration tester with one or two motor driven USP/EP/JP compliant test station. The compact unit of our light series is equipped with an integrated flow-through heater and a moulded one-piece PET water bath (no leaking / breaking, easy to clean) with cover.
The ZT 120 light series can be easily operated via a membrane keypad. Defined test run parameters such as run time and water bath temperature are entered with symbol keys and the actual values are then shown on large and bright LED displays. The run-time counter automatically starts as soon as the basket rack assembly is lowered into the test media.
Specifications
- 1 or two test stations, driven by a single motor
- 30 ± 1 strokes/min.
- 55 ± 2 mm stroke height
- Function keys and 2x LED display for entering nominal bath temperature and required run-time
- Starts/stops to counting run-time automatically when basket rack is lowered
- Integrated flow-through heating system (accuracy ± 0.2 °C)
- Temperature range 30 - 50 °C
- Run time up to 9 h, 59 min, 59 s ± 1 s
- Manual lift-in and -out of the baskets
ZT 320 hajoamismittalaite
On the ZT 320 disintegration testers series, the test stations (one to four) are driven individually. In order to guarantee outstanding quality and the highest ease of use each test station is controlled by its own keypad. After programming the required test run time, the basket rack assembly with its loaded samples is automatically lowered into the media. On completion of the preset run time or when the stop button is pressed, the basket rack is raised from the media to prevent further disintegration of the samples (optional).
The temperature displayed on the LED display is the one measured by the standard external temperature sensor, either located inside the water bath or the test media. The optional type “B” basket rack assembly with three larger test tubes can be fitted to all ZT 220/320 disintegration testers.
Optionally the basket rack assembly is moved into the media when the start button is pressed and automatically raised on completion of the preset run time or when the stop button is pressed. All recorded test run parameters can be hard copied via the USB printer interface. The actual disintegration time can be added manually afterwards.
The ZT 320 series can also be equipped with 100 % USP/EP/JP compliant “Quick-Clean” basket racks and type “B” baskets with three larger test tubes. Of course all required validation handbooks and tools as well as ERWEKA PQ tablets with specified disintegration times are available.
Options – ZT 320 Series is customizable to your needs
- Baskets type A (6 glass tubes) or type B (3 larger glass tubes)
- Automated lift-in and lift-out of the basket rack assembly/ies on start/completion of the preset run time of each test station. This option guarantees that the disintegration of the samples cannot go on when the preset run time is completed.
- Media pre-heat and disintegration rack storage container located in the water bath (ZT 321 and 323 only)
- “Quick-Clean” basket (100 % USP/EP/JP compliant) for fast cleaning of the test stations. No tools required for assembly and disassembly.
- Baskets with three test stations with an inner diameter of 30 mm, according EP, type “B”
- Water stabiliser with colour indicator
ZT 730 hajoamismittalaite
The ERWEKA ZT 730 Series with cable-free AirBasket automatically determines the disintegration time of samples by using a unique system of magnets and sensors. The ZT 730 is available with one (ZT 731) or two (ZT 732) individually driven test stations and is equipped with an integrated flow-through heater.
Its newly designed, cable-free AirBasket makes disintegration testing with automatic determination of the disintegration time as easy and fast as possible. Its electronics compartment is sealed, making it dishwasher proof. It‘s sensors are also highly durable and enable the AirBasket to be used in acidic media. AirBasket is available as type A basket with 6 test tubes for standard tablets, or type B basket with 3 test tubes for bigger tablets (according to USP/EP standards).
The reliable waterbath technology utilizes the thermal inertia of water to create a steady temperature for testing according to USP/EP standards. Its temperature sensor PT 100 allows constant control of the waterbath temperature. The ZT 730 series is controlled through an intuitive 7″ touch-screen and is capable of storing and retrieving up to 200 products/methods with results and parameters.
Specifications
- 1 (ZT 731) or 2 (ZT 732) test stations
- 7″ touch display
- 4 GB memory for 100 products/methods and approx. 1 million test results
- 30 ± 1 strokes/min
- 55 ± 2 mm stroke height
- AirBasket type A (6 test tubes) or AirBasket type B (3 test tubes)
- Integrated flow-through heating system)
- External PT 100 temperature sensor
Options – ZT 730 is available with different options.
- AirBasket type A (6 test tubes) & type B (3 test tubes)
- Additional vessel for pre-heating (ZT 731 only)
- Disc remover for removal of type A discs from the basket
- Mesh 40 sieves for AirBasket type A & B
- Printer
- IQ/OQ/PV documents
- IQ/OQ/PV validation service
Vakuumin vuototestauslaite
VDT
The VDT/S is a vacuum leak tester for blisters and other packaging forms. The maximum vacuum (absolute pressure range up to 100 mbar) and the vacuum hold time before release can be easily set via the symbol keypad. The actual vacuum is continuously displayed on the LED display. Test run parameters such as actual/set vacuum value and hold time can be simply documented via a usb interface or a connected printer.
Leak Testing
For checking the density the ERWEKA VDT/S performs a methylene blue dye test, which is divided into several phases. During the pressure maintenance phase the blisters are exposed to a vacuum, which is generated in the vacuum container. Afterwards the container is ventilated.
In the subsequent penetration process the blister is resting in the methylene blue solution, so that the solution can suck into any imperfectly sealed packaging.
The integrated vacuum pump can be recalibrated using the optional validation kit which includes a vacuummeter, type DVR.
Options – small but versatile
- 150 mm diameter container
- 200 mm diameter container
- 250 mm diameter container
- 300 mm diameter container
- Validation tool kit, certified, for VDT/S comprising of:
- Vacuummeter type DVR
- Stop watch
- IQ/OQ handbook
- Spare parts kit
Kulumisen mittauslaite
TAR
The TAR series is a USP/EP/JP compliant ERWEKA unit for testing friability and/or abrasion. Programming is easily performed by the symbol style keypad. The rotation speed can be programmed between 20 and 100 rpm and test run duration can be set in either time or total number of revolutions. During the test run, the actual rotation speed and the remaining test run duration are shown on bright LED displays. For larger samples, the complete unit can be set to the USP/EP required 10° position by a standard switching leg.
To increase the ease of handling on the TAR series, the friability drums do not have to be removed and opened for loading and emptying. Instead the friability drums can be effortlessly filled and emptied through a special opening. On completion of a test run, the samples are automatically removed into a container located under the drums.
The USB interface allows you to print-out the test parameters (time, actual/nominal speed) when a printer is connected.
Options
- Friability drum, left (TAR 120/220)
- Friability drum with opening, left (TAR 120/220)
- Friability drum with opening, left, certified (TAR 120/220)
- Friability drum with opening, right (TAR 220)
- Friability drum with opening, right, certified (TAR 220)
- Abrasion drum, left (TAR 120/220)
- Abrasion drum, right (TAR 220)
- Qualification handbook
- Qualification tool-kit
Pulverin tiheyden mittalaite
SVM II
The SVM II is our latest generation of tapped density tester. With unprecedented flexbility and intelligent features, it makes tapped density testing as easy and reliable as never before.
The 7“ high resolution touch display with a modern user interface focuses the user on the most important task the new SVM II has to fullfill – 100% USP/EP compliant tapped density testing. With the automatic calculation features of the TestAssist, the user is guided step-by-step through the testing process as quickly as possible. It also automatically calculates the Hausner Ratio and compressibility index and prints the reports after every test.
In addition to its ease of use, the SVM II is the most flexible tapped density tester we ever built. The newly designed SwitchPlate system enables 5 different versions of the SVM II, with both USP 1 and USP 2 in either one or two test station configurations or a combination with both methods. And the best part – they can also be upgraded at a later time point!
SVM II also supports a variety of method and norms: From USP 1 and USP 2 to ASTM B527-15 and DIN EN ISO 787-11:1995 – with the SVM II, users are on the safe side of valid and conform tapped density testing.
Key Features – 5 Variations, intelligent SwitchPlate System and TestAssist
The new SVM II offers the same flexibility as its 5 predecessor models. It can test for USP method 1 and method 2 and can be equipped with either one or two test stations of the same method or a combination of both. Optional changing from one variant to another can be done by the user within minutes. This makes the SVM II the most flexible tapped density tester we ever built.
Innovative
With the innovative SwitchPlate system, the SVM II is as flexible as ever before. Available SwitchPlates:
- USP 1 with 1 station
- USP 1 with 2 stations
- USP 2 with 1 station
- USP 2 with 2 stations
- 2 station combination with USP 1 and USP 2
TestAssist – Tapped density testing easier than ever!
TestAssist is a comprehensive, yet simple wizard for the quick execution of tapped density testing. The user is guided step by step through the parameterisation, whereby incorrect entries are prevented by TestAssist. As soon as the tapped density test is running, the test screen displays all important status information about the test at any time.
When testing according to USP methods, TestAssist prompts the user to enter the required values. Afterwards, it then computes the results for Tapped Density, Hausner Ratio and Compressibility Index completly automatically.
With the help of the intelligent TestAssist, tapped density testing is as easy and fast as ever before!
The SVM II Touch Interface with TestAssist
The touch interface of the SVM II focuses the user on the most important task to be done with the SVM II: tapped density testing. The central part is the TestAssist, an intelligent assistant with realtime feasability checks that provides support and guarantees the conformity of the entered parameters according to USP/EP/JP. Tapped density testing thus becomes simple and safe. But we didn‘t stop at TestAssist – all other functions, such as the control panel, the qualification menu or the service menu, are also designed to connect user and hardware as quickly as possible.
Specifications
- Height, width, depth: 196.5 mm / 300 mm / 326 mm
- Weight: 17 kg
- Voltage: 115/230 V; 50/60 Hz
- Fuses: 1A
- USB A/B, Ethernet, RS232
- USP method 1: 300±15 taps/min; tap height 14±2mm
- USP method 2: 250±15 taps/min; tap height 3±0.2mm
- EP 2.9.34 Bulk density and tapped density of powders
- ASTM B527-15 Tap density of metal powders and compounds
- DIN EN ISO 787-11:1995 General test methods, pigments and fillers
- 10 reports (temporarily)
Rakeiden virtausmittalaiteet
SMG
The manual ERWEKA SMG 697 is the unit for the reproducible determination of apparent bulk density, which can be used with all free flowing powders or granules. According to DIN ISO 697, the apparent bulk density is determined by measuring the mass of powder in a receiver of known dimension after filling from a funnel of a specified shape under specified conditions.
Included in the delivery are the apparatus SMG 697, operating instructions and a calibration certificate.
Specifications
- Height: 280 mm
- Width: 210 mm
- Depth: 147 mm
- Weight: 7.5 kg
- Material: 1.4305 / 1.4571
- Receiver: 500 ml
GT Sarjan garanulaattien virtausmittalaiteet
The devices of the ERWEKA granulate flow tester family were developed to determine the flow behavior of powders and granules using various measurement methods.
As an entry-level device, the GTL is ideally suited for the USP/EP-compliant measurement of the flowability of powder and granules according to the measurement methods of weight and volume. Thanks to the simple numerical membrane keypad and the LC display, the device is easy to operate and all results can also be printed out.
The GT has a scale – this allows the stable weight to be measured during the flow process. In addition to the two measurement methods of the GTL (flowability by weight and volume), the GT can also measure the flowability over a specified time as well as the flow angle with graphic display.
The GTB complements the extensive capabilities of the GT with an advanced, automatic laser measurement of the angle of repose – this gives the user a comprehensive picture of the flow properties of the evaluated powder or granulate.
Both devices, the GT and the GTB have an LC display and a membrane keypad for easy operation, which also enables the results to be printed out. Various accessories also make it possible to carry out customer-specific measurements that are not EP-compliant. For example, outlet nozzles with different diameters or smaller receiving funnels can be selected. The GT and GTB can optionally be equipped with a stirring unit for samples with poor flowability. The speed can be regulated in four stages.
Suppositorio mittauslaitteet
ST 35
The ERWEKA suppository disintegration tester ST 35 comes with three turning test stations, each located inside a four liter glass vessel with an optional magnetic stirrer. Additionally, the unit contains a thermostatically heated water bath (non-leaking and double secured), in which the test stations are placed.
The test stations are automatically turned 180° in adjustable intervals.
The ST 35 features an integrated “high-power” flow-through heating system (accuracy ± 0.2° C) and an internal temperature sensor for temperature display.
Test time and nominal bath temperature are easily entered via the membrane keys. Current test time as well as actual water temperature are shown on clearly visible red LEDs.
On request, an alarm may be selected to sound upon completion of the preset test time. Due to the width of the ST 35, the test stations can be easily separated to facilitate the cleaning process. Optionally, separately controllable magnetic stirrers can be placed in each test station (glass beaker) to get the required hydrodynamics.
Options
- Set of three magnetic stirrers, controlled by the membrane keys of the unit
- Water stabiliser with colour indicator, one bottle for two fillings
SBT 32 supon kovuuden mittauslaite
The suppository hardness tester (type SBT 2) consists of an electrically heated chamber with an integrated sample holder and a number of interchangeable plastic inserts to accept various sized suppositories. Once up to the desired temperature, the hardness is checked by weights (included in the standard delivery range) which are gradually placed on the device until the suppository collapses under the load of the added weights.
The results are expressed in terms of total weight required to bring about the collapse of the suppository.
ST 35 supon sulamisaika mittalaite
The ERWEKA SSP measures the melting point of suppository samples.
It consists of a graduated tube with an integrated test chamber made of glass. The sample to be tested is placed in the spiral shaped glass test basket inside the test chamber, which is surrounded by a water jacket.
The water inside the jacket can be simply heated by the optional circulation
Options
- ERWEKA circulation heater EST 2
- IQ/OQ documents
PM 30 supon pehmiämis mittauslaite
The ERWEKA PM 30 measures the softening time of suppositories. Suppositories must disintegrate, dissolve or melt at body temperature in order to release their active ingredients to the body. ERWEKA offers a version for EP method A and method B.
The PM 30 penetration tester (compliant to EP, Apparatus A) and the PM 3 (acc. to EP, App. B) have been designed to carry out reproducible measurements regarding the softening time of suppositories at predetermined temperatures. The construction of the tester makes visual observation of the melting characteristics extremely simple. In total, the unit comprises of three test stations.
Options
- Glass test tubes, 2 g, with adaptor, for PM 30 acc. to EP App. B
- Glass test tubes, 3 g, with adaptor, for PM 30 acc. to EP App. B
- Immersion thermometer with certificate (instead of non-certificated immersion thermometer)
- Water stabiliser with colour indicator, one bottle for two fillings
